Frontline Top Spot for dogs and cats is a typical monthly flea and tick medication prescribed quite often by veterinarians. The Frontline Top Spot medication kills cent percent the existing fleas on your pet within 24 hours of application on its body. Besides, it is also effective against ticks of all life stages, including the brown dog tick, the American dog tick, the lone star tick and the deer tick (which are the major carriers of Lyme disease).
| Pet | Weight | Dosage |
| Dogs/Puppies: (8 weeks of age or older) | Up to 22 lbs | Apply contents of 1 applicator once a month (0.67 ml) |
| 23-44 lbs | Apply contents of 1 applicator once a month (1.34 ml) | |
| 45-88 lbs | Apply contents of 1 applicator once a month (2.68 ml) | |
| 89-132 lbs | Apply contents of 1 applicator once a month (4.02 ml) | |
| Cats/Kittens: (8 weeks of age or older) | All weights | Apply contents of 1 applicator once a month (0.5 ml) |