Advantage Multi for dogs and cats is an effective pet medicine, which kills a fleas and treats infections. It is a topical monthly application and is a combination of parasiticide (moxidectin) and insecticide (imidacloprid). It is well known for prevention of heartworm and controls many different flea infection, whipworms, hookworms and roundworms in dogs, whereas, in cats it is known for preventing heartworms and treating fleas infection, hookworms, ear mites and roundworms. It works quite effectively. Its active ingredient namely moxidectin disrupt the nerve transmission which results in parasite’s paralysis and death. And the other ingredient imidacloprid attacks fleas and results in its paralysis and death.